P22 Viral Capsids as Nanocomposite High-Relaxivity MRI Contrast Agents
نویسندگان
چکیده
منابع مشابه
P22 viral capsids as nanocomposite high-relaxivity MRI contrast agents.
Attachment of multiple chelated Gd(3+) ions to the interior of bacteriophage P22 viral capsids affords nanoscale MRI contrast agents with extremely high relaxivity values. Highly fenestrated "wiffleball" morphology is unique to P22 and assures water exchange between the environment and interior cavity of the capsid. The cavity of P22 "wiffleball" was functionalized with a branched oligomer comp...
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ژورنال
عنوان ژورنال: Molecular Pharmaceutics
سال: 2012
ISSN: 1543-8384,1543-8392
DOI: 10.1021/mp300208g